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Disclosure: The author holds a long position in SDGR.
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SDGR

Analysis as of: 2026-01-06
Schrödinger, Inc.
Schrödinger sells molecular simulation and informatics software and monetizes its platform through drug-discovery collaborations and a therapeutics pipeline.
ai biotech cloud healthcare software
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Summary

From niche modeling to molecular R&D platform
The core bet is enterprise standardization: making computational workflows the default operating layer for drug teams, with higher recurring revenue mix. Upside comes from disciplined therapeutics optionality that does not reintroduce late-stage cash burn.

Analysis

Thesis
SDGR can re-rate from “scientific tools + lumpy milestones” to a higher-trust molecular R&D operating system by pushing workflows into hosted/usage delivery, packaging auditability/security as a paid tier, and keeping therapeutics option value partner-funded—compounding software visibility while preserving biotech upside.
Last Economy Alignment
Strong fit: it sells cognition-compressing software into pharma R&D, where speed, trust, provenance, and workflow lock-in become the moat.
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Opportunity Outlook

Average Implied 5-Year Multiple
3.7x (from 5 most recent analyses)
Reasoning
The upside is not a single biotech catalyst; it’s repeatable enterprise expansion. If Schrödinger shifts more customers to hosted delivery, attaches premium “trust” features (auditability/security), and productizes collaboration economics without re-adding late-stage clinical burn, revenue becomes more recurring/visible and deserves a modest multiple expansion versus today’s niche-tools framing.
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Risk Assessment

Overall Risk Summary
The key risks are (1) enterprise adoption speed (pharma scale-up timing), (2) software commoditization/bundling by broader informatics and AI stacks, and (3) strategic drift back toward capital-intensive clinical development that would reintroduce dilution and compress valuation.
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Third Party Analyst Consensus

12-Month Price Target
$27.22
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