Beam’s upside is real, but the path is narrow and milestone-driven. The biggest risks are whether
risto-cel clears the regulatory handoff on time, whether
BEAM-302 shows enough
durability and safety for a true
registrational path, and whether Beam can translate clinical differentiation into treatment-center throughput and repeatable manufacturing quality. Cash and Sixth Street support help, but they do not remove the core proof burden.